8 players have pulled out of the England squad with various injuries. Amongst them are: Alexander-Arnold, Saka, Foden and Declan Rice. The 4 mentioned there are regular starters. So England won't be at full strength come game-time. They still obviously have quality all over the pitch, but it should make getting a result a touch easier.
Remember a draw is enough to guarantee us top spot, with one game to spare.